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1.CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
390 points by gmays 4 hours ago | hide | 102 comments
2.I Am Not a Reverse Centaur (miguelgrinberg.com)
108 points by ibobev 1 hour ago | hide | 66 comments
3.How to Setup a Local Coding Agent on macOS (ikyle.me)
75 points by kkm 1 hour ago | hide | 23 comments
4.Malware developers added nuclear and biological weapons text to to their spyware (twitter.com/jsrailton)
123 points by marc__1 3 hours ago | hide | 82 comments
5.Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
65 points by iweczek 2 hours ago | hide | 26 comments
6.A PDF that changes based on how its read (sgaud.com)
74 points by SarthakGaud 3 hours ago | hide | 33 comments
7.Slightly reducing the sloppiness of AI generated front end (envs.net)
124 points by FergusArgyll 4 hours ago | hide | 80 comments
8.Looking Forward to Postgres 19: It's About Time (pgedge.com)
69 points by xngbuilds 2 hours ago | hide | 19 comments
9.A dumpster arrived behind my university's library (yalereview.org)
123 points by mooreds 5 hours ago | hide | 97 comments
10.Law Enforcement's "Warrior" Problem (2015) (harvardlawreview.org)
34 points by bookofjoe 2 hours ago | hide | 31 comments
11.Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
72 points by ibobev 4 hours ago | hide | 43 comments
12.There Is Life Before Main in Rust (grack.com)
35 points by mmastrac 3 hours ago | hide | 10 comments
13.A Peter Thiel-Backed Tribunal Is Putting Journalists on Trial (hollywoodreporter.com)
47 points by cdrnsf 52 minutes ago | hide | 11 comments
14.Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
17 points by arcb 2 hours ago | hide | 6 comments
15.AI agent bankrupted their operator while trying to scan DN42 (lantian.pub)
1323 points by xiaoyu2006 14 hours ago | hide | 475 comments
16.Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (yadutaf.fr)
37 points by jtlebigot 4 hours ago | hide | 8 comments
17.Maxproof (arxiv.org)
114 points by ilreb 7 hours ago | hide | 8 comments
18.Cosmodial Sky Atlas (killedbyapixel.github.io)
10 points by memalign 1 hour ago | hide | 1 comment
19.Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
6 hours ago | hide
20.A Call to Action: Stop the FCC's KYC Regime (lopp.net)
274 points by FergusArgyll 4 hours ago | hide | 175 comments
21.I Won't Buy You a Coffee (hakkerman.eu)
42 points by speckx 55 minutes ago | hide | 34 comments
22.WASI 0.3 (bytecodealliance.org)
198 points by mavdol04 5 hours ago | hide | 80 comments
23.Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
28 points by datafreak_ 4 hours ago | hide | 8 comments
24.Keygen.music (keygen.music)
106 points by soupspaces 3 hours ago | hide | 62 comments
25.If you are asking for human attention, demonstrate human effort (tombedor.dev)
1394 points by jjfoooo4 20 hours ago | hide | 440 comments
26.New privacy frontier: Europe eyes crackdown on smart glasses (politico.com)
53 points by 1vuio0pswjnm7 2 hours ago | hide | 31 comments
27.How we made hit video game Prince of Persia (theguardian.com)
250 points by msephton 16 hours ago | hide | 101 comments
28.Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
49 points by _____k 7 hours ago | hide | 5 comments
29."Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
94 points by speckx 1 hour ago | hide | 91 comments
30.Show HN: Script to bulk delete Claude chats from the web UI (github.com/matteoleonesi)
43 points by ML0037 4 hours ago | hide | 14 comments

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