| 1. | | Baby is healed with first personalized gene-editing treatment (nytimes.com) |
| 1257 points by jbredeche on May 15, 2025 | 531 comments |
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| 2. | | Human (quarter--mile.com) |
| 737 points by surprisetalk on May 15, 2025 | 269 comments |
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| 3. | | Internet Artifacts (neal.fun) |
| 693 points by mikerg87 on May 13, 2025 | 140 comments |
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| 4. | | Malicious compliance by booking an available meeting room (clientserver.dev) |
| 375 points by jakevoytko on May 15, 2025 | 367 comments |
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| 5. | | A Tiny Boltzmann Machine (eoinmurray.info) |
| 262 points by anomancer on May 15, 2025 | 47 comments |
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| 6. | | The unreasonable effectiveness of an LLM agent loop with tool use (sketch.dev) |
| 447 points by crawshaw on May 15, 2025 | 320 comments |
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| 7. | | A leap year check in three instructions (hueffner.de) |
| 434 points by gnabgib on May 15, 2025 | 164 comments |
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| 8. | | Coinbase says hackers bribed staff to steal customer data, demanding $20M ransom (cnbc.com) |
| 422 points by gpi on May 15, 2025 | 499 comments |
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| 9. | | Changes since congestion pricing started in New York (nytimes.com) |
| 442 points by Vinnl on May 13, 2025 | 706 comments |
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| 10. | | Show HN: Min.js style compression of tech docs for LLM context (github.com/marv1nnnnn) |
| 177 points by marv1nnnnn on May 15, 2025 | 52 comments |
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| 11. | | LLMs get lost in multi-turn conversation (arxiv.org) |
| 374 points by simonpure on May 15, 2025 | 259 comments |
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| 12. | | Python lib generates its code on-the-fly based on usage (github.com/cofob) |
| 247 points by klntsky on May 12, 2025 | 88 comments |
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| 13. | | Tek – A music making program for 24-bit Unicode terminals (codeberg.org/unspeaker) |
| 173 points by smartmic on May 15, 2025 | 23 comments |
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| 14. | | Working on complex systems: What I learned working at Google (thecoder.cafe) |
| 302 points by 0xKelsey on May 13, 2025 | 143 comments |
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| 15. | | Initialization in C++ is bonkers (2017) (tartanllama.xyz) |
| 191 points by todsacerdoti on May 15, 2025 | 249 comments |
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| 16. | | Launch HN: Tinfoil (YC X25): Verifiable Privacy for Cloud AI |
| 146 points by FrasiertheLion on May 15, 2025 | 100 comments |
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| 17. | | I don't like NumPy (dynomight.net) |
| 488 points by MinimalAction on May 15, 2025 | 206 comments |
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| 18. | | Migrating to Postgres (usemotion.com) |
| 241 points by shenli3514 on May 14, 2025 | 274 comments |
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| 19. | | The current state of TLA⁺ development (ahelwer.ca) |
| 142 points by todsacerdoti on May 15, 2025 | 42 comments |
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| 20. | | Pathfinding (juhrjuhr.itch.io) |
| 155 points by sebg on May 15, 2025 | 46 comments |
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| 21. | | NASA Stennis's first open source software (nasa.gov) |
| 78 points by mindcrime on May 13, 2025 | 32 comments |
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| 22. | | Dr. Dobb's Journal interviews Jef Raskin (1986) (computeradsfromthepast.substack.com) |
| 91 points by rbanffy on May 15, 2025 | 79 comments |
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| 23. | | Lua for Elixir (davelucia.com) |
| 211 points by davydog187 on May 13, 2025 | 82 comments |
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| 24. | | Windsurf SWE-1: Our First Frontier Models (windsurf.com) |
| 190 points by arittr on May 15, 2025 | 62 comments |
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| 25. | | Show HN: Real-Time Gaussian Splatting (github.com/axbycc) |
| 144 points by markisus on May 15, 2025 | 53 comments |
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| 26. | | Internet Scrabble Club (2002-) (isc.ro) |
| 55 points by indigodaddy on May 11, 2025 | 24 comments |
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| 27. | | In the US, a rotating detonation rocket engine takes flight (arstechnica.com) |
| 115 points by LorenDB on May 15, 2025 | 73 comments |
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| 28. | | “The Mind in the Wheel” lays out a new foundation for the science of mind (experimental-history.com) |
| 125 points by CharlesW on May 15, 2025 | 89 comments |
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| 29. | | Self-hostable webhook tester in go (testwebhook.xyz) |
| 76 points by muliswilliam on May 13, 2025 | 15 comments |
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| 30. | | Wavelet Trees: An Introduction (2011) (alexbowe.com) |
| 56 points by Tomte on May 15, 2025 | 16 comments |
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| More |
